Transmission of Toxoplasmosis by Leukocyte (WBC) Transfusion

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Transmission of toxoplasmosis by leukocyte transfusion.

S TUDIES IN RABBITS HAVE SHOWN that the protozoan Toxoplasma gondii is able to parasitize peripheral blood leukocytes.’ In humans, parasitemia caused by this organism has been demonstrated in an asymptomatic blood donor,2 and in a woman who delivered a congenitally infected infant.3 Despite these observations, no cases of acute toxoplasmosis acquired via transfusion of blood products have been ...

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Toxoplasmosis as a complication of transfusion in hemodialysis patients

Background Toxoplasma Gondi is an obligate intracellular protozoan parasite that is one of the most important protozoa of blood and tissue. The medical importance of this parasite is considered from two aspects of congenital defects and opportunities among those with congenital immune deficiency. Depending on the mode of transmission through blood and the risk of infection to Toxoplasma Gondi...

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Attempts to detect infectivity in the blood of humans and animals affected with transmissible spongiform encephalopathies (TSEs or prion diseases) have often been inconclusive because of the limitations of cross-species bioassays and the small volumes of blood that can be injected by the intracerebral route. A model has been developed for the experimental study of TSE transmission by blood tran...

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It is now clearly established that the transfusion of blood from variant CJD (v-CJD) infected individuals can transmit the disease. Since the number of asymptomatic infected donors remains unresolved, inter-individual v-CJD transmission through blood and blood derived products is a major public health concern. Current risk assessments for transmission of v-CJD by blood and blood derived product...

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Transfusion transmission of parasites

Blood recipients in the United States (US) generally face a low risk of being transfused with a component contaminated with parasites. Quantifying the risk often depends on parameters that are unknown or poorly characterized, but estimates have remained stable in recent years at one transmission of parasitic infection per million transfusions. This round figure obscures divergent trends for som...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1970

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197009000-00107